Table 1.
Reported cagA genotypes and vacA s, m, and i regions genotypes and cagA status in studies used in the present meta-analysis
| |
|
|
|
|
cagA genotype |
vacA genotype |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Area/country | Authors | Year | Patients (n)* | cagA | ABC | ABCC/ABCCC | ABD | 2a | 1a | s1 (n/%) | s2 (n/%) | m1 (n/%) | m2 (n/%) | i1 (n/%) | i2 (n/%) |
| Vietnam |
Yamaoka Y
[7] |
2002 |
25 S |
24 (96) |
NA |
NA |
NA |
0 (0) |
24 (100) |
25 (100) |
0 (0) |
14 (56) |
11 (44) |
NA |
NA |
| Vietnam |
Uchida T
[31] |
2009 |
103 S |
98 (95) |
4 (4) |
0 (0) |
94 (96) |
NA |
NA |
103 (100) |
1 (1) |
44 (45) |
54 (55) |
NA |
NA |
| Vietnam |
Truong BX
[32]] |
2009 |
22 S |
22 (100) |
1 (5) |
0 (0) |
21 (95) |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
| Vietnam |
Nguyen TL
[33] |
2010 |
100 |
95 (95) |
NA |
NA |
NA |
NA |
NA |
100 (100) |
0 (0) |
48 (48) |
52 (52) |
94 (94) |
6 (6) |
| Thailand |
Yamaoka Y
[7] |
2002 |
8 S |
8 (100) |
NA |
NA |
NA |
4 (50) |
4 (50) |
8 (100) |
0 (0) |
6 (75) |
2 (25) |
NA |
NA |
| Thailand |
Vilaichone RK
[34] |
2004 |
98 S |
98 (100) |
NA |
NA |
NA |
50 (51) |
48 (49) |
98 (100) |
0 (0) |
71 (72) |
27 (28) |
NA |
NA |
| Thailand |
Linpisarn S
[35] |
2007 |
135 |
119 (88) |
NA |
NA |
NA |
NA |
NA |
132 (100) |
0 (0) |
73 (63) |
42 (37) |
NA |
NA |
| Thailand |
Chomvarin C
[36] |
2008 |
112 S |
110 (98) |
NA |
NA |
NA |
NA |
NA |
112 (100) |
0 (0) |
65 (58) |
47 (42) |
NA |
NA |
| Malaysia |
Tan HJ
[37] |
2005 |
127 S |
107 (84) |
NA |
NA |
NA |
NA |
NA |
117 (92) |
10 (8) |
81 (64) |
46 (36) |
NA |
NA |
| Malaysia |
Tan HJ
[38] |
2006 |
73 S |
58 (79) |
NA |
NA |
NA |
NA |
NA |
65 (89) |
8 (11) |
46 (63) |
27 (37) |
NA |
NA |
| Malaysia |
Mohamed R
[39] |
2009 |
93 |
NA |
23 (22) |
13 (12) |
70 (66) |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
| Malaysia |
Schmidt HMA
[40] |
2009 |
126 S |
NA |
34 (28) |
19 (16) |
68 (56) |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
| Malaysia |
Schmidt HMA
[41] |
2010 |
159 S |
159 (100) |
71 (45) |
0 (0) |
88 (55) |
NA |
NA |
155 (97) |
4 (3) |
94 (59) |
65 (41) |
154 (97) |
5 (3) |
| Singapore | Zheng PY [42] | 2000 | 108 S | 95 (88) | NA | NA | NA | NA | NA | 103 (99) | 1 (1) | 39 (38) | 65(62) | NA | NA |
‘NA’ (not available) indicates a lack of data associating cagA status, EPIYA motif genotype, and vacA s-, m-, and i-region genotypes.
The uppercase ‘s’ indicates the use of single colonies and the remaining studies refer to the use of gastric biopsy samples, paraffin-embedded biopsy samples, and pools of cultured colonies.