Table 1.
Characteristics of included studies
| Author | Country (ethnicity) | Cases/controls | Diagnosis of cases | Selection of controls |
|---|---|---|---|---|
| Selvaraj |
India (Asian) |
210/120 |
Smear, culture, radiological, clinical response confirmed PTB |
Normal healthy spouses and Tuberculosis Research Centre staff, ethnicity and area of residence matched |
| Fitness |
Malawi (African) |
181/533 |
Smear, culture, histology confirmed TB, HIV negative |
No history or symptom of TB; not first or second degree relatives of the cases; age, sex and area of residence matched |
| Vejbaesya |
Thailand (Asian) |
149/147 |
Smear, culture, clinical and radiological response confirmed PTB, HIV negative |
Unrelated healthy blood bank donors |
| Ates |
Turkey (Caucasian) |
128/80 |
Smear, culture, pathological, radiological , clinical response confirmed PTB,EPTB |
No history of TB noted on chest radiography, age and sex matched |
| Trajkov |
Republic of Macedonia (Caucasian) |
75/301 |
Smear/culture confirmed PTB |
No family history of TB, nationality and area of residence matched |
| Merza |
Iran (Asian) |
117/60 |
Smear and radiological confirmed PTB |
Nurses, doctors and TB staff with no laboratory or clinical sign of diseases development, age, sex and nationality matched |
| Sharma |
India (Asian) |
185/155 |
Smear, culture, histology, radiological , clinical response confirmed PTB,EPTB,HIV negative without chronic illness |
Without a family history of TB or any other related disease and a possibility of a latent tuberculosis infection, socioeconomic status and ethnicity matched |
| Anoosheh |
Iran (Asian) |
93/103 |
Smear and culture confirmed PTB |
No history of TB |
| Lin | China (Asian) | 46/40 | Pathological examination and clinical response confirmed EPTB | NR |
*NR=not reported; HIV = human immunodeficiency virus; PTB= pulmonary tuberculosis; TB = tuberculosis; EPTB= extrapulmonary tuberculosis; HWE= Hardy–Weinberg equilibrium.