Table 2. Haplotype frequencies in breast cancer patients and healthy controls.
Haplotype | Freq. | Breast Cancer (n = 491) | Healthy Controls (n = 502) | P value |
TA | 0.556 | 0.576 | 0.528 | 0.0062a |
GC | 0.199 | 0.188 | 0.207 | 0.4232 |
GA | 0.149 | 0.140 | 0.155 | 0.4447 |
TC | 0.097 | 0.078 | 0.114 | 0.0093b |
The haplotypes shown occurred with a frequency of ≥10% in the case-control population.
P = 0.0179 and
P = 0.0259 after correcting the P-value for multiple testing with the Haploview program using 10,000 permutations.