Table 3. Serum Antibody Responses to Influenza A (H7N7) Vaccinations1.
Post Dose 1 | Post Dose 2 | |||||||||
No. (%) ≥4-Fold Increase | No. (%) ≥1∶40 | No. (%) ≥4-Fold Increase | No.(%) ≥1∶40 | |||||||
Dosage (µg HA)2 | No.3 | HAI4 | Neut4 | HAI4 | Neut4 | No.3 | HAI4 | Neut4 | HAI4 | Neut4 |
0 | 25 | 0 | 0 | 0 | 0 | 25 | 0 | 0 | 0 | 0 |
7.5 | 25 | 0 | 0 | 0 | 0 | 24 | 0 | 0 | 0 | 0 |
15 | 24 | 0 | 1 (4) | 0 | 1 (4) | 24 | 0 | 1 (4) | 0 | 1 (4) |
45 | 25 | 0 | 0 | 0 | 0 | 24 | 0 | 2 (8) | 0 | 2 (8) |
90 | 25 | 0 | 0 | 0 | 0 | 21 | 1 (5) | 2 (10) | 1 (5) | 2 (10) |
As determined at central laboratory; increase defined as ≥4-fold or <10 to 40.
As determined in single radial immunodiffusion assays.
Number of subjects in evaluation.
Hemagglutination-inhibition (HAI) and neutralizing (neut) antibody assays at central laboratory.