Table 1. The MTDH (−470G>A) genotype & Allele distribution in Ovarian Cancer and controls.
Genotype | Ovarian Cancer n(%)† | Controls n(%)† | P-value | OR 95%CI |
GG | 93(64.1) | 141(55.5) | 0.042 | 1.00 (reference) |
GA | 47(32.4) | 88(34.6) | 0.81 (0.52 ∼1.26) | |
AA | 5(3.45) | 25(9.84) | 0.30 (0.11 ∼0.82) | |
GG+GA | 140(96.6 ) | 229(90.2 ) | 0.0198 | 1.00 (reference) |
AA | 5(3.45 ) | 25(9.84 ) | 0.33 (0.12 ∼0.87) | |
GG | 93(64.1 ) | 141(55.5 ) | 0.0924 | 1.00 (reference) |
GA+AA | 52(35.9 ) | 113(44.5 ) | 0.70 (0.46 ∼1.06) | |
G | 233(80.3 ) | 370(72.8 ) | 0.01756 | 1.00 (reference) |
A | 57(19.7 ) | 138(27.2 ) | 0.66 (0.46 ∼0.93) |
The X2 for HWE of Ovarian Cancer group and control group is 0.1 and 3.94 respectively (both P>0.05).