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. 2012 Dec 11;7(12):e51572. doi: 10.1371/journal.pone.0051572

Table 4. SBI Genotyping on human and bovine isolates of EHEC O157.

SBI Genotype Codinga Bovine (%) Human (%) Total (%) SBI Genogroupb P-valueb Former SBI genotype designation (%)c
WY12 92 (40.5) 97 (50.5) 189 (45.1) CG 0.048 3 (91), 7 (6.4), 18 (2.1), 22 (0.5)
AY2 11 (4.8) 47 (24.5) 58 (13.8) CG <0.0001 1 (96.6), 19 (3.5)
SY2c 45 (19.8) 2 (1.0) 47 (11.2) BBG <0.0001 5 (87.2), 1 (10.6), 19 (2.1)
ASY12c 38 (16.7) 8 (4.2) 46 (11.0) BBG <0.0001 6 (100)
ASY22c 5 (2.2) 15 (7.8) 20 (4.8) CG 0.01 1 (85), 5 (15)
SY12c 14 (6.2) 0 (0.0) 14 (3.3) BBG 0.0004 6 (92.9), 16 (7.1)
ASY2 1 (0.4) 12 (6.3) 13 (3.1) CG 0.0005 1 (100)
W2 3 (1.3) 8 (4.2) 11 (2.6) Unclassified 0.12 4 (100)
WY2 4 (1.8) 0 (0.0) 4 (1.0) Unclassified N/A 2 (100)
Y 4 (1.8) 0 (0.0) 4 (1.0) Unclassified N/A 17 (75), 10 (25)
ASY2c 2 (0.9) 0 (0.0) 2 (0.5) Unclassified N/A 5 (100)
AWY12 1 (0.4) 1 (0.5) 2(0.5) Unclassified N/A 3, 18
AY 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 10 (100)
Y1 0 (0.0) 1 (0.5) 1 (0.2) Unclassified N/A 8 (100)
ASY1 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 13 (100)
AY1 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 13 (100)
WY1 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 22 (100)
SWY2c 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 12 (100)
0 (0.0) 1 (0.5) 1 (0.2) Unclassified N/A 9 (100)
SY122c 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 6 (100)
AWY2 1 (0.4) 0 (0.0) 1 (0.2) Unclassified N/A 2 (100)
Total 227 192 419
a

Concatenation of presence of specific bacteriophage at argW, sbcB, wrbA or yehV locations designated by uppercase first letter of each insertion site (A, S, W or Y,) followed by the presence of stx1, stx2a or stx2c denoted by 1,2 or 2c.

b

The SBI Genotypes that are significantly over-represented among cattle isolates as compared to human isolates are referred as bovine-biased genotypes (BBG); the SBI Genotypes that show significantly over-representation/similar-representation among human isolates as compared to cattle isolates are referred as clinical genotypes (CG); the SBI genotypes that could not be evaluated for a bovine association due to small numbers (1–4 isolates) are designated “unclassified” genotypes in this manuscript (Fisher’s exact test P≤0.05).

c

Percent of isolates belonging to most common previously defined SBI genotype [5], [10], [14].