Table 1. Characteristics of study population.
CRC Cases | Controls | |
Characteristic | N (%) | N (%) |
Female | 122 (48.4) | 356 (42.1) |
Male | 130 (51.6) | 490 (57.9) |
Age (in years) – mean(SD) | 63.4 (8.4)/64.1 (8.3) | 64.3 (8.2) |
rs1800734 genotype | ||
Homozygous wild-type (GG) | 150 (59.5) | 528 (62.5) |
Heterozygous (GA) | 96 (38.1) | 264 (31.2) |
Homozygous variant (AA) | 6 (2.4) | 53 (6.3) |
rs749072 genotype | ||
Homozygous wild-type (AA) | 122 (51.9) | 438 (51.8) |
Heterozygous (AG) | 104 (44.3) | 271 (32.0) |
Homozygous variant (GG) | 9 (3.8) | 57 (6.7) |
rs13098279 genotype | ||
Homozygous wild-type (GG) | 147 (62.6) | 491 (64.1) |
Heterozygous (GA) | 84 (35.7) | 233 (27.5) |
Homozygous variant (AA) | 4 (1.7) | 42 (5.5) |
Distribution of clinicopathological features in primary colorectal carcinomas and controls from Ontario. Age at study recruitment is indicated for CRC cases and controls. Blood was drawn an average of less than one year and no more than six years after study recruitment.
SD = standard deviation.