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. 2012 Dec 11;7(12):e51461. doi: 10.1371/journal.pone.0051461

Figure 1. SM-164 induces rapid cIAP-1 degradation and displays modest single-agent effect in HCC cells.

Figure 1

(a–d). BEL-7402, SMMC-7721, HepG2 and Hep3B cell lines were treated with SM-164 at 0.1 µM for 1, 6 and 24 h. Whole cell lysates were examined for the expressions of cIAP-1 and XIAP by western blotting analysis and specific antibodies. β-Actin was used as a loading control. (e-h). BEL-7402, SMMC-7721, HepG2 and Hep3B cell lines were treated with SM-164 for 4 d, cell viability inhibition was determined using an MTT assay.