Table 1. HEK293 proteins increased >95% confidencea.
| Accession | HGNC | Name | 6h L:H ratiob | 24h L:H ratiob |
| Proteins measured in >1 experiment (at a single time point) | ||||
| 34416 | LTF | Lactotransferrin | 8.88 | 8.72 |
| 6013427 | ALBU | serum albumin precursor | 5.85 | 5.02 |
| 17318569 | K2C1 | keratin 1 | 4.80 | 38.35 |
| 1683637 | BAD | Bcl-2 binding component 6 | 3.50 | 0.76 |
| 25058739 | ALB | ALB protein | 3.00 | |
| 9963783 | Q9HBZ9 | RNA helicase | 2.71 | 2.51 |
| 4557325 | APOE | apolipoprotein E precursor | 2.68 | 6.48 |
| 6563288 | UBQL2 | ubiquitin-like product Chap1/Dsk2 | 2.67 | 1.00 |
| 16553095 | ASPC1 | unnamed protein product | 2.39 | 2.41 |
| 56204388 | MEA1 | male-enhanced antigen | 2.27 | 0.88 |
| 20336350 | HCD2 | endoplasmic reticulum-associated amyloid beta peptide-binding protein | 2.22 | 1.86 |
| 4885217 | XPF | excision repair cross-complementing rodent repair deficiency, complementation group 4 | 2.08 | |
| 55959029 | UBE2T | ubiquitin conjugating enzyme | 2.03 | 1.19 |
| 22671717 | HBA2 | hemoglobin alpha-2 | 2.02 | 3.58 |
| 55660909 | SC23B | Sec23 homolog B (S. cerevisiae) | 2.00 | 1.21 |
| 29792115 | SMAD3 | SMAD, mothers against DPP homolog 3 (Drosophila) | 1.99 | 2.01 |
| 48734878 | Q6IPH7 | RPL14 protein | 1.97 | 1.85 |
| 7020506 | UB2R2 | unnamed protein product | 1.96 | 1.08 |
| 4505571 | SQSTM | sequestosome 1 | 1.84 | 1.39 |
| 57208697 | REPS1 | RALBP1 associated Eps domain containing 1 | 1.77 | 1.70 |
| 14042287 | NRBP | unnamed protein product | 1.74 | 1.02 |
| 4589628 | PALLD | KIAA0992 protein | 1.73 | |
| 55962212 | CTBP2 | C-terminal binding protein 2 | 1.72 | 0.72 |
| 55749758 | DIP2B | DIP2 disco-interacting protein 2 homolog B | 1.64 | 1.36 |
| 5803123 | PSMF1 | proteasome inhibitor subunit 1 isoform 1 | 1.64 | 1.56 |
| 21961219 | DNJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 1.64 | 0.88 |
| 12654999 | DPOA2 | Polymerase (DNA directed), alpha 2 (70kD subunit) | 1.63 | 0.94 |
| 13543689 | SLD5 | GINS complex subunit 4 (Sld5 homolog) | 1.60 | |
| 793843 | RL29 | ribosomal protein L29 | 1.57 | 1.67 |
| 3970842 | AL1A2 | RALDH2 | 1.57 | 1.36 |
| 56202415 | STX12 | syntaxin 12 | 1.54 | 1.18 |
| 28336 | ACTB | mutant beta-actin (beta'-actin) | 1.53 | 1.46 |
| 56205198 | SNAPN | SNAP-associated protein | 1.53 | 1.01 |
| 55962100 | B1AN89 | eukaryotic translation initiation factor 4 gamma, 3 | 1.51 | 0.94 |
| 13477351 | CP080 | Gene trap locus 3 (mouse) | 1.50 | 0.95 |
| 54696534 | ATPO | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 1.50 | 1.59 |
| 7705411 | YTHDF2 | YTH domain family, member 2 | 1.47 | 0.99 |
| 9623363 | DPOE3 | DNA polymerase epsilon p17 subunit | 1.46 | |
| 55962775 | S10AD | S100 calcium binding protein A13 | 1.38 | 1.34 |
| 7672784 | HSP7E | heat shock protein HSP60 | 1.37 | 1.75 |
| 7576229 | VIME | vimentin | 1.35 | 0.99 |
| 21749793 | Q8NB80 | unnamed protein product | 1.31 | 0.82 |
| 7705431 | CCD72 | coiled-coil domain containing 72 | 1.30 | |
| 48146451 | DBNL | HIP-55 | 1.29 | 1.18 |
| 21750170 | Q8NB11 | unnamed protein product | 1.28 | 1.29 |
| 55663125 | SET | SET nuclear oncogene | 1.26 | 0.95 |
| 9966827 | PCNP | PEST-containing nuclear protein | 1.21 | 1.92 |
| 6633995 | SK2L2 | KIAA0052 protein | 1.16 | 2.13 |
| 6274552 | STAT1 | signal transducer and activator of transcription 1 isoform alpha | 1.11 | 2.38 |
| 56203909 | DDI2 | DNA-damage inducible protein 2 (DDI2) | 1.09 | 1.90 |
| 862457 | ECHA | enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase alpha-subunit of trifunctional protein | 1.04 | 1.81 |
| 34532659 | Q6ZTT1 | unnamed protein product | 1.03 | 1.46 |
| 5738608 | NFU1 | HIRA-interacting protein HIRIP5 | 1.00 | 1.65 |
| 3287825 | DC1L2 | Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC53/55) (LIC-2) | 0.93 | 1.56 |
| 31652283 | ACO13 | thioesterase superfamily member 2 | 0.87 | 1.65 |
| 31880783 | PELO | pelota homolog | 0.77 | 1.40 |
| 18490917 | SCG2 | Secretogranin II (chromogranin C) | 7.62 | |
| 4731861 | OAS3 | 2′–5′oligoadenylate synthetase 3 | 5.46 | |
| 14550514 | ISG15 | ISG15 ubiquitin-like modifier | 4.27 | |
| 34192824 | IFIT2 | Interferon-induced protein with tetratricopeptide repeats 2 | 3.57 | |
| 2653424 | SHIP2 | inositol polyphosphate 5-phosphatase | 2.44 | |
| 49574526 | IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 2.21 | |
| 47123412 | Q6NSF2 | RPLP0 protein | 1.91 | |
| 51476787 | Q68D64 | hypothetical protein | 1.45 | |
| 51476787 | Q68D64 | hypothetical protein | 1.45 | |
a
Protein is included if at least half of the biologic z-score values are ≥1.960σ (indicated by bolding) and there are no major disagreements between biological replicates.
b
L/H ratio refers to the geometric mean of all log2 L/H values for each given gi number, expressed as relative protein quantity in infected cultures.