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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Chromosoma. 2012 Oct 14;121(6):629–642. doi: 10.1007/s00412-012-0387-4

Figure 8.

Figure 8

Calpain 4 knockdown reduces cisplatin-induced nucleolar localization of coilin in HeLa cells. Cells were transfected with control or calpain-targeted siRNA. 32 hr post-transfection, cells were treated with cisplatin. 48hr post-transfection, cells were fixed and immunostained for coilin (green), calpain 4 (red) and nuclei were stained with DAPI (blue). Arrows indicate cells with normal Cajal body localization of coilin and arrowheads indicate cells containing significant nucleolar coilin.