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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: J Invest Dermatol. 2012 Sep 6;133(2):553–561. doi: 10.1038/jid.2012.326

Figure 4. MSC-FMB implantation times and hair regrowth.

Figure 4

a) 1.5×106 MSC-FMB were implanted into C3H mice wounds immediately after 2 days of loading onto FMB or after being expanded for a further 5 days in vitro. C3H mice were pre-irradiated with 4Gy/WBI + 21Gy/SI and WTS was assessed after 4 weeks of healing. Error bars indicate mean+/−SEM, n=4. Significance: *P<0.05, **P<0.01 by Student’s t-test. b) Skin in C3H mice irradiated with 4Gy/WBI + 21Gy/SI and implanted with MSC-FMB regrew hair by 3 weeks after treatment, although color was not restored. (WTS: wound tensile strength; MSC: Marrow Stromal Cells; FMB: Fibrin Microbeads; TD: Total deficit)