Table 5.
Association of changes of Ped-ANAM scores and ranges cognitive ability based on formal neuropsychological testing over an 18 month period in 24 cSLE-Patients§
| Ped-ANAM scores# | Ped-ANAM Subtest* | Working Memory | Psychomotor Speed | Attention | Visuoconstructional Ability |
|---|---|---|---|---|---|
| AC | Code Substitution Delayed | - | 0.30 | - | - |
| Code Substitution | 0.25 | - | - | - | |
| Continuous Performance Test | - | 0.34 | 0.51 | - | |
| Logical Relations | - | -0.23 | - | 0.21 | |
| Matching to Sample | 0.30 | - | 0.28 | 0.34 | |
| Matching Grids | - | - | -0.24 | - | |
| Mathematical Processing | - | - | 0.51 | - | |
| Procedural Reaction Time | 0.39 | - | 0.32 | 0.51 | |
| Spatial Processing | 0.52 | 0.20 | - | 0.36 | |
| Sternberg Memory Search | - | 0.29 | - | - | |
| CVc | Code Substitution Delayed | - | - | - | - |
| Code Substitution | - | - | -0.43 | -0.25 | |
| Continuous Performance Test | -0.28 | - | -0.51 | -0.45 | |
| Logical Relations | -0.26 | - | -0.31 | -0.22 | |
| Matching to Sample | -0.41 | - | - | -0.27 | |
| Matching Grids | - | - | - | - | |
| Mathematical Processing | - | 0.24 | -0.26 | - | |
| Procedural Reaction Time | -0.38 | - | - | -0.49 | |
| Spatial Processing | -0.22 | -0.21 | - | - | |
| Sternberg Memory Search | - | -0.25 | -0.31 | - | |
| MNc | Code Substitution Delayed | - | - | - | - |
| Code Substitution | - | - | - | - | |
| Continuous Performance Test | - | 0.25 | -0.23 | - | |
| Logical Relations | - | - | - | - | |
| Matching to Sample | - | - | -0.40 | -0.40 | |
| Matching Grids | - | - | -0.25 | - | |
| Mathematical Processing | - | - | - | - | |
| Procedural Reaction Time | - | - | - | - | |
| Spatial Processing | - | - | -0.24 | - | |
| Sternberg Memory Search | - | -0.23 | -0.26 | - | |
| Simple Reaction Time | - | -0.20 | - | - | |
#
Accuracy or AC = Percentage of correct responses per subtest; Consistency CVc = SD of reaction time for a correct response / MNc; MNc = Mean reaction time for correct response
§
Values are Spearmen correlation coefficients. Ped-ANAM change score and changes in z-scores per cognitive domain during formal neuropsychological testing; only values of r > |0.2| are shown and r > |0.4| are statistically significant at p < 0.05.