Figure 5.

Pulmonary tumour nodules and pulmonary metastatic tumour weight in mice vaccinated with BMP-V vaccine through various routes of administration. Mice (n=5) were challenged with TC-1 cells through the tail vein. On day 4, mice were randomised and treated with 20 μg BMP-V in 0.1 ml PBS or PBS alone. The same treatments were repeated on days 8 and 12. All of the mice were killed on day 25. (a) Pulmonary metastatic tumour weights were measured. ^*P<0.05 compared with the PBS group. (b) Data are presented as the mean number of pulmonary tumour nodules±s.d. of five mice per group in a representative experiment. ^*Indicates P<0.05 compared with the PBS group. (c) Gross picture of pulmonary tumours in each vaccinated group. Experiments were repeated in duplicate with similar results.