Table 1.

NADPH Oxidases in the Brain

	Brain Region	Specie	RNA	Protein	References
Nox1	Medulla	Human		+	[85]
	Superior colliculus	Rat	+		[26]
	Hippocampus	Rat	+		[84]
	Cerebellum	Rat	+		[83]
	Forebrain	Mice	+		[25]
	Midbrain	Mice	+		[25]
	Hindbrain	Mice	+		[25]
	Dorsal root ganglion	Mice	+		[86]
	Hypothalamus	Mice	+		[87]
Nox2	Medulla	Human/Rat		+	[74,83]
	Superior colliculus	Rat	+		[26]
	Thalamus	Mice/Rat	+	+	[26, 78]
	Hippocampus	Mice/Rat/Human	+	+	[58, 69, 70, 88, 90]
	Cerebellum	Mice		+	[80]
	Forebrain	Mice	+		[25]
	Midbrain	Mice	+		[25]
	Hindbrain	Mice	+		[25]
	Hypothalamus	Mice/Rat	+	+	[73, 74, 76]
	Substantia nigra	Mice/Rat	+	+	[ 75, 77]
	Amygdala	Mice		+	[78]
	Nucleus of the solitary tract	Rat		+	[79]
	Striatum	Mice/Rat	+	+	[71, 72,75]
	Cortex	Mice/Rat/Human	+	+	[24, 69, 89, 90]
	Brainstem	Mice		+	[70]
Nox3	Cerebellum	Rat	+		[81, 83]
	Hypothalamus	Rat	+		[81]
	Cortex	Rat	+		[81]
Nox4	Superior colliculus	Rat	+		[26]
	Hypothalamus	Mice		+	[73]
	Cortex	Mice	+	+	[61, 82]
	Forebrain	Mice	+		[25]
	Midbrain	Mice	+		[25]
	Hindbrain	Mice	+		[25]
	Hippocampus	Mice	+	+	[82]
	Cerebellum	Mice	+	+	[82]

Observation: several studies that reported Nox protein occurrence by immunostaining have not actually used the appropriate negative controls, and therefore the data must be interpreted with caution.