Table 1.
Summary of the presence of HFOs, resections, and surgical outcome
Surgical procedure |
Pathology |
|||||||
---|---|---|---|---|---|---|---|---|
No./total | % | Temporal | ExtraT. | Multilobar | FCD | TSC | Other | |
Total No. patients identified | 48 | |||||||
Total No. patients included in this study | 44 | |||||||
Presence of ictal HFOs (*p = 0.001) | 41/44 | 93 | ||||||
Complete HFOs resection | 22/41 | 54 | ||||||
Surgical outcome | ||||||||
Seizure-free | 18/22 | 82 | 6 | 5 | 7 | 12 | 5 | 1 (chronic inflammation) |
>90% | 2/22 | 9 | 1 | 0 | 1 | 2 | 0 | 0 |
>50% | 2/22 | 9 | 0 | 2 | 0 | 0 | 2 | 0 |
No improvement | 0/22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incomplete HFO resection | 19/41 | 46 | ||||||
Surgical outcome | ||||||||
Seizure-free | 4/19 | 21 | 0 | 2 | 2 | 3 | 1 | 0 |
>90% | 4/19 | 21 | 0 | 3 | 1 | 3 | 0 | 1 (subpial gliosis) |
>50% | 6/19 | 32 | 2 | 2 | 2 | 6 | 0 | 0 |
No improvement | 5/19 | 26 | 1 | 1 | 3 | 5 | 0 | 0 |
No HFOs presence | 3/44 | 7 | ||||||
Surgical outcome | ||||||||
Seizure-free | 1/3 | 0 | 1 | 0 | 3 | 0 | 0 | |
>90% | 1/3 | 1 | 0 | 0 | 0 | 0 | 0 | |
>50% | 1/3 | 1 | 0 | 0 | 0 | 0 | 0 |
HFOs, high-frequency oscillations; SOZ, seizure-onset zone; ExtraT., extratemporal; FCD, focal cortical dysplasia; TSC, tuberous sclerosis complex; >90%, >90% seizure reduction; >50%, >50% seizure reduction.
p-value: Fisher's exact test – two sided p-value.