Table 4.
Disease Status at Baseline | Incidence Rate* by Number of Retinal Signs
|
HR† | 95% CI | P-value | |
---|---|---|---|---|---|
≥ 2 Retinal Signs n (%) | < 2 Retinal Signs n (%) | ||||
By Diabetes Status | |||||
Absent | 24 / 241 (9.9) | 263 / 3812 (6.9) | 1.33 | 1.06–1.68 | 0.015 |
Present | 6 / 57 (10.6) | 47 / 568 (8.3) | 1.54 | 0.65–3.68 | 0.325 |
By Cardiovascular Disease Status | |||||
Absent | 23 / 231 (10.0) | 229 / 3340 (6.9) | 1.35 | 1.00–1.82 | 0.051 |
Present | 7 / 67 (10.4) | 81 / 1040 (7.8) | 1.25 | 0.62–2.50 | 0.531 |
Abbreviations: CI, confidence interval; HR, hazard ratio.
Incidence rate was presented in the number of disability per total person-years (the number of disability per 100 person-years).
Adjusted for age, gender, white race, current smoking, body mass index, systolic blood pressure, total cholesterol, natural logarithm of C-reactive protein, natural logarithm of internal carotid artery intima-media thickness, antihypertensive medication use, lipid-lowering medication use, and self-reported disability in performing instrumental activities of daily living at baseline, plus prevalent cardiovascular disease (for diabetes analysis) and diabetes status (for cardiovascular disease analysis).