Association signals are shown for all single nucleotide polymorphisms (SNPs) genotyped in (A) screening-stage samples (black circles), (B) replication-stage samples (blue circles), and (C) for combined screening- and replication-stage samples (red circles). The most associated SNPs, rs11931074 and rs3857059, lie in or near the SNCA gene, and are in complete linkage disequilibrium. The plot were generated using the SNP. plotter package within R version 2.6.1.