Table 3.
Multivariable Analysis of Liver Death in HIV-Infected Individuals
| Variable | IRR | 95% CI | P Value |
|---|---|---|---|
| Hepatitis status | |||
| HCV | 1 | ||
| HBV | 2.2 | 1.1–4.5 | .03 |
| Older age | |||
| Per 10-year increase | 1.6 | 1.1–2.3 | .01 |
| Latest CD 4 count | |||
| >350 cells/mm3 | 1 | ||
| 200–350 cells/mm3 | 7.0 | 2.4–20.1 | <.001 |
| <200 cells/mm3 | 16.2 | 6.1–42.8 | <.001 |
| HAART | |||
| Never | 1 | ||
| Ever | 0.7 | .3–1.6 | .43 |
| Recruitment period | |||
| Before 2001 | 1 | ||
| 2001–2003 | 0.8 | .2–2.3 | .64 |
Adjusted for race and cumulative alcohol use. Age, CD4 cell count, cumulative alcohol use, and highly active antiretroviral therapy use included as time updated covariates.
Abbreviations: CI, confidence interval; HAART, highly active antiretroviral therapy; HBV, hepatitis B virus; HCV, hepatitis C virus; HIV, human immunodeficiency virus; IRR, incidence rate ratio.