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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: Pediatr Blood Cancer. 2011 Jan 19;58(1):31–36. doi: 10.1002/pbc.22964

Table III.

Multivariate analyses of correlates of insulin resistance (estimated by the Homeostasis Model of Insulin Resistance) in 116 survivors of childhood acute lymphoblastic leukemia.

Females Males
N=64 N=52

Measurements intercept β 95%CI P intercept β 95%CI P
Leptin: adiponectin ratio 0.93 0.13 0.06–0.19 <0.01 0.55 0.17 0.10–0.23 <0.01
Body mass index (mg/kg2) 0.44 0.04 0.02–0.05 <0.01 −0.14 0.05 0.04–0.07 <0.01
Waist circumference (cm) 0.08 0.02 0.008–0.02 <0.01 −0.47 0.02 0.01–0.03 <0.01
Percent body fat (by DXA)* −0.07 0.03 0.01–0.05 <0.01 0.27 0.03 0.02–0.05 <0.01
Visceral adiposity (by CT)** 1.02 1.98 1.23–2.73 <0.01 1.15 1.46 0.82–2.01 <0.01
Lean body mass (kg) 0.13 0.03 0.02–0.05 <0.01 0.23 0.02 0.002–0.03 0.02
*

DXA: Dual-energy x-ray absorptiometry scan;

**

CT: Computed tomography;

P-value adjusting for Cranial radiation therapy, race/ethnicity, age at diagnosis, and interval from cancer diagnosis