Table 2.
Bivariate and Multivariate Associations Between Receipt of IPTp-SP and Pregnancy Outcomes
Overall | Suboptimal IPTp | Full IPTp | P Value (Unadjusted) | P Value (Adjusted)a | |
---|---|---|---|---|---|
Maternal parasite density, parasites/μL median (IQR) | 526 (60–3495) | 780 (105–8370) | 226 (49–2118) | .014 | .349 |
Placental parasite density, parasites/μL median (IQR) | 1069 (73–9185) | 4898 (300–13 800) | 168 (52–1072) | <.001 | .659 |
P values determined by linear regression. Parasite densities were natural log-transformed prior to inclusion in regression models.
Abbreviations: IPTp, intermittent preventive therapy with antimalarials during pregnancy; IQR, interquartile range; SP, sulfadoxine-pyrimethamine.
a Adjusted for gravidity, human immunodeficiency virus infection, delivery year, and Plasmodium falciparum dhfr-dhps haplotype.