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. 2012 Dec 6;4:361–374. doi: 10.2147/CEOR.S37458

Table S4.

Treatment response rates of bevacizumab and photodynamic therapy for the treatment of age-related macular degeneration

Author Year Definition of treatment response IVB PDT RR (95% CI)


No of responses No of nonresponses No of responses No of nonresponses
Lazic and Gabric20 2007 0.2 increase in logMAR 1 53 0 50 2.78 (0.12–66.75)
Bashshur et al19 2007 3rd-line increase in Snellen fraction 16 16 5 25 3.00 (1.25–7.17)
Sacu et al22 2009 15-letter increase in ETDRS score 4 10 1 13 4.00 (0.51–31.46)
Parodi et al21 2010 15-letter increase in ETDRS score 7 12 1 17 6.63 (0.90–48.69)
Pooled RR (95% CI) 3.44 (1.67–7.1)

Abbreviations: CI, confidence interval; IVB, intravitreal bevacizumab; PDT, photodynamic therapy; RR, relative risk; ETDRS, Early Treatment Diabetic Retinopathy Study; logMAR, logarithm of the minimum angle of resolution.