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. 2012 Dec 6;4:361–374. doi: 10.2147/CEOR.S37458

Table S6.

Mean change of visual acuity and central macular thickness after receiving ranibizumab and bevacizumab for the treatment of age-related macular degeneration

Author Year IVR IVB


n Mean SD n Mean SD
VA (ETDRS letter score)
Martin et al25 2011 285 6.80 13.10 271 5.90 15.70
Gharbiya et al24 2010 16 17.31 11.10 16 15.87 8.41
Biswas et al23 2011 54 3.56 8.90 50 3.96 8.36
Subramanian et al26 2010 7 6.29 13.74 15 7.53 15.32
USMD (95% CI) 0.49 (95% CI, −1.37 to 2.34)
CMT (μm)
Martin et al25 2011 285 −168.0 186.00 271 −152.00 178.00
Biswas et al23 2011 54 −44.7 66.56 50 −37.96 55.33
Subramanian et al26 2009 7 −102.0 72.90 13 −35.00 80.50
USMD (95% CI) −14.18 (95% CI, −32.06 to 3.70)

Abbreviations: CI, confidence interval; CMT, central macular thickness; IVB, intravitreal bevacizumab; IVR, intravitreal ranibizumab; SD, standard deviation; USMD, unstandardized mean difference; VA, visual acuity; ETDRS, Early Treatment Diabetic Retinopathy Study.