Table 1.
Electrophysiological analysis of action potential parameter, TRPV1, and TRPV4 current properties.
| Con (n = 39) | CFA (n = 30) | EA (n = 28) | |
|---|---|---|---|
| Resting membrane potential (mV) | −46.70 ± 1.72 | −44.60 ± 1.42 | −42.04 ± 2.41 |
| Capacitance (pF) | 35.39 ± 1.83 | 37.29 ± 1.84 | 37.93 ± 4.29 |
| AP threshold (mV) | −19.93 ± 1.35 | −25.04 ± 2.58** | −17.66 ± 2.86# |
| AP rheobase (pA) | 483.03 ± 41.80 | 401.83 ± 22.92* | 600.10 ± 58.79## |
| AP amplitude (mV) | 78.35 ± 2.28 | 73.82 ± 3.31 | 74.79 ± 4.74 |
| AP rise time (ms) | 2.30 ± 0.11 | 2.07 ± 0.02* | 2.49 ± 0.14## |
| AP fall time (ms) | 6.36 ± 0.37 | 3.96 ± 0.39** | 8.41 ± 2.28# |
| AHP (ms) | 71.69 ± 8.24 | 60.22 ± 9.43 | 77.14 ± 10.14 |
| TRPV1% | 20.51 | 30 | 14.29 |
| TRPV4% | 17.95 | 33.33 | 17.85 |
| TRPV1 amplitude (pA) | 90.79 ± 12.99 | 189.53 ± 39.38* | 67.74 ± 11.53# |
| TRPV4 amplitude (pA) | 99.35 ± 14.54 | 374.24 ± 108.59* | 129.48 ± 24.93# |
*P < 0.05 compared with the control group; **P < 0.01 compared with the control group; # P < 0.05 between the inflammation and EA groups; ## P < 0.01 between the inflammation and EA groups. Con: control; CFA: complete Freund's adjuvant; EA: electroacupuncture; AP: action potential; AHP: afterhyperpolarization.