Table 4.
Analysis results for the effect (risk difference) of hs-CRP from the ARIC study. The model is adjusted for age, sex, race, smoking status, systolic blood pressure, LDL-C, HDL-C, and diabetes
| Time-invariant weight |
Time-varying weight |
|||||
|---|---|---|---|---|---|---|
| Variable | Estimate (×105) | SE (×105) | p-value | Estimate (×105) | SE (×105) | p-value |
| For the CHD event | ||||||
| CRP2 | 0.991 | 0.360 | 0.006 | 0.974 | 0.373 | 0.009 |
| CRP3 | 1.770 | 0.464 | <0.001 | 1.693 | 0.460 | <0.001 |
| CRP2*(LDL-C <130) | −1.021 | 0.427 | 0.017 | −1.038 | 0.443 | 0.019 |
| CRP3*(LDL-C <130) | −1.204 | 0.511 | 0.019 | −1.147 | 0.504 | 0.023 |
| For the stroke event | ||||||
| CRP2 | −0.327 | 0.150 | 0.029 | −0.274 | 0.153 | 0.073 |
| CRP3 | −0.409 | 0.159 | 0.010 | −0.331 | 0.159 | 0.040 |
| CRP2*(LDL-C <130) | 0.243 | 0.249 | 0.329 | 0.216 | 0.259 | 0.405 |
| CRP3*(LDL-C <130) | 0.170 | 0.252 | 0.501 | 0.141 | 0.254 | 0.578 |
| CRP2*(t>1069) | 0.255 | 0.121 | 0.035 | 0.247 | 0.118 | 0.035 |
| CRP3*(t>1069) | 0.603 | 0.120 | <0.001 | 0.576 | 0.110 | <0.001 |