. 2013 Jan;54(1):152–163. doi: 10.1194/jlr.M030700

TABLE 3.

Fasting metabolic panel assessed incrementally during the study

Diet	Week 8	Week 12	Week 16	Week 20
Glucose (mmol/l)
AIN-76A	9.2 ± .4^a	9.1 ± 0.7^a	7.5 ± 0.5^a&	7.7 ± 0.6^b&
AIN-76A Mod	8.6 ± 0.4^a	8.4 ± 0.7^a	7.7 ± 0.6^a&	6.1 ± 0.3^b&
6%-SF	9.0 ± 0.5	11.2 ± 1.4	10.9 ± .9^#	10.3 ± 0.5^{^%}
12%-SF	9.1 ± 0.6^a	9.6 ± 0.9^a	10.4 ± 0.7^ab#	12.0 ± 1.1^b%
24%-SF	8.5 ± 0.4	9.6 ± 0.7	10.3 ± 0.7^#	8.5 ± 0.5^{& ^}
Insulin (pmol/l)
AIN-76A	150 ± 15	115 ± 5	120 ± 5^&	200 ± 30^&
AIN-76A Mod	135 ± 15	180 ± 20	160 ± 30^&	165 ± 25^&
6%-SF	130 ± 30^a	225 ± 31^a	395 ± 75^b#	560 ± 105^{c^}
12%-SF	150 ± 25^a	245 ± 30^b	580 ± 80^{c^}	615 ± 75^{c^}
24%-SF	165 ± 25^a	205 ± 20^a	330 ± 20^b#	395 ± 55^b#
HOMA (unit)
AIN-76A	10.1 ± 0.7	8.1 ± 0.7	6.6 ± 0.5^&	12.3 ± 2.5^&
AIN-76A Mod	8.6 ± 0.9	11.4 ± 0.9	10.2 ± 2.2^&	7.7 ± 1.1^&
6%-SF	7.3 ± 1.6^a	16.4 ± 2.7^a	26.8 ± 4.2^b#	36.8 ± 6.1^c%
12%-SF	9.0 ± 2.2^a	16.3 ± 2.7^a	46.7 ± 7.0^{b^}	57.8 ± 11.0^{c^}
24%-SF	10.3 ± 1.4^a	15.2 ± 2.3^ac	25.6 ± 2.6^bc#	24.5 ± 3.0^bd#
TC (mmol/l)
AIN-76A	3.79 ± 0.10^a&	4.10 ± 0.06^ab&	3.94 ± 0.09^ab&	4.34 ± 0.24^b&
AIN-76A Mod	3.76 ± 0.04^a&	4.25 ± 0.11^b&#	4.47 ± 0.14^b#	4.13 ± 0.19^b&
6%-SF	4.09 ± 0.11^a&#	4.64 ± 0.10^b#	4.96 ± 0.13^{c^}	5.52 ± 0.16^{d#^}
12%-SF	4.32 ± 0.15^a#	4.70 ± 0.12^b#	5.12 ± 0.15^{c^}	5.61 ± 0.15^{d^}
24%-SF	4.10 ± 0.06^a&#	4.51 ± 0.17^b&#	4.83 ± 0.15^{bc#^}	5.14 ± 0.08^c#
LDL-C (mmol/l)
AIN-76A			0.93 ± 0.04^&	0.99 ± 0.08^&
AIN-76A Mod			1.22 ± 0.09^#	1.08 ± 0.11^&
6%-SF			1.65 ± 0.06^{^}	1.73 ± 0.08^{^}
12%-SF			1.75 ± 0.07^{^}	1.80 ± 0.11^{^}
24%-SF			1.68 ± 0.09^{^}	1.77 ± 0.07^{^}
HDL-C (mmol/l)
AIN-76A	1.35 ± 0.06^&	1.44 ± 0.08	1.42 ± 0.09^&#	1.47 ± 0.08^&#
AIN-76A Mod	1.31 ± 0.08^&	1.37 ± 0.09	1.42 ± 0.06^&#	1.43 ± 0.06^&#
6%-SF	1.43 ± 0.06^&#	1.45 ± 0.06	1.44 ± 0.07^&	1.43 ± 0.07^&#
12%-SF	1.32 ± 0.06^&	1.41 ± 0.10	1.35 ± 0.12^&	1.25 ± 0.05^&
24%-SF	1.61 ± 0.05^#	1.59 ± 0.06	1.66 ± 0.06^#	1.66 ± 0.06^#
TC/HDL-C ratio (unit)
AIN-76A	2.8 ± 0.1	2.9 ± 0.2	3.0 ± 0.2	3.0 ± 0.1^&
AIN-76A Mod	3.0 ± 0.3	3.0 ± 0.1	3.1 ± 0.2	3.0 ± 0.2^&
6%-SF	2.9 ± 0.1^a	3.3 ± 0.2^ab	3.6 ± 0.3^b	3.9 ± 0.3^b#
12%-SF	3.3 ± 0.2^a	3.5 ± 0.4^a	3.7 ± 0.3^a	4.3 ± 0.3^b#
24%-SF	2.6 ± 0.1	2.9 ± 0.2	2.9 ± 0.2	3.1 ± 0.2^&
Triglycerides (mmol/l)
AIN-76A	0.8 ± 0.02	0.8 ± 1.4	0.8 ± 0.01	0.8 ± 0.04^&
AIN-76A Mod	0.7 ± 0.01^a	0.7 ± 0.03^ab	0.8 ± 0.03^b	0.7 ± 0.03^a#
6%-SF	0.7 ± 0.02^a	0.7 ± 0.01^ab	0.8 ± 0.03^b	0.8 ± 0.01^b&
12%-SF	0.8 ± 0.03	0.8 ± 0.03	0.8 ± 0.03	0.8 ± 0.02^&
24%-SF	0.8 ± 0.01^a	0.8 ± 0.03^ab	0.9 ± 0.03^bc	0.9 ± 0.04^{c^}

Fasting metabolic panel assessed in weeks 8, 12, 16, and 20 (n = 8–9). Values not sharing a superscripted letter (a, b, c) differ significantly over time within the group (P ≤ 0.05). Values not sharing a superscripted symbol (^&#^%) differ significantly among groups within the given week (P ≤ 0.05).