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A: Far-ultraviolet CD spectra of wild-type and mutant apoE3 forms. Spectra are averages of three separate experiments. B: Percent helical content calculated based on the molar ellipticity at 222 nm as described in Materials and Methods. Error bars indicate SD calculated from three separate experiments. *P = 0.0015, **P < 10−6, ***P < 10−6.
