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. 2013 Jan;54(1):244–253. doi: 10.1194/jlr.M031732

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Copyright © 2013 by the American Society for Biochemistry and Molecular Biology, Inc.

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Fig. 4. — Linoleate ester:free sterol ratio determined for SLOS plasmas by LC-MS-MS. A: Ratio for cholesterol linoleate:total cholesterol, 7-DHC-linoleate/total 7-DHC, and 8-DHC-linoleate/total 8-DHC in plasma of SLOS patients. B: Plot of cholesterol linoleate versus total cholesterol in plasma of SLOS patients. C: Plot of 7-dehydrocholesterol linoleate versus total 7-dehydrocholesterol in plasma of SLOS patients. D: Plot of 8-dehydrocholesterol linoleate versus total 8-dehydrocholesterol in plasma of SLOS patients. Samples shown in orange are from patients undergoing simvastatin treatment. Removal of these samples from the data does not significantly alter the correlations.