Gene expression in the mesenteric fat of WT and guanylin-GC-C double-Tg rats. (A, B) Quantitative RT-PCR analysis of mRNA transcripts of genes associated with (A) adipocyte maturation and droplet formation and (B) fatty acid oxidation in mesenteric adipose tissue. Data were normalized to the GAPDH mRNA levels and are presented as means ± SEM (n = 4 or 5). *P < 0.05 compared with value for WT rats on the same diet. Acadam, acyl-CoA dehydrogenase C4 to C12 straight-chain; Acadl, acyl-CoA dehydrogenase long chain; Acox1, acyl-CoA oxidase 1 palmitoyl; Adipoq, adiponectin; C/EBPα, CCAAT-enhancer-binding protein α; Cpt1a, carnitine palmitoyltransferase 1a; GLUT4, glucose transporter 4; PPARγ, peroxisome proliferator-activated receptor γ.