Table 3. Comet Assay Data for Mice Exposed to Acrylamide.

Dose (mg/kg)	Number of Animals	% Tail DNA		Tail Length (Microns)		Olive Tail Moment
		Mean	S.E.	Mean	S.E.	Mean	S.E.
Blood
0	5	8.7	0.77	2.8	0.53	0.2	0.03
12.5	4	20.0	2.73	7.5	1.70	0.6a	0.07
25.0	4	19.8	2.38	8.6	1.77	0.7a	0.17
37.5	4	20.7	1.26	9.8	1.16	0.9a	0.07
50.0	5	25.4	2.80	9.8	0.84	1.1a	0.16
Trend Testb:						p < 0.0001
Liver
0	5	14.2	1.40	24.5	2.68	2.4	0.33
12.5	5	20.3	0.89	33.9	1.77	3.8a	0.37
25.0	5	27.2	2.26	40.4	1.53	6.0a	0.70
37.5	5	24.9	1.30	40.9	1.99	5.2a	0.50
50.0	5	27.9	0.92	38.3	1.83	5.8a	0.33
Trend Testb:						p < 0.0001
Duodenum
0	5	17.0	1.48	24.6	3.01	2.6	0.31
12.5	5	32.8	2.59	45.6	2.78	6.9a	0.74
25.0	5	42.5	4.84	53.8	6.41	10.8a	2.15
37.5	5	41.3	4.13	53.0	6.09	10.8a	2.12
50.0	5	44.1	3.85	57.7	3.53	11.4a	1.35
Trend Testb:						p = 0.0003
Testes - Germ Cells
0	5	7.0	0.72	14.3	1.12	0.8	0.13
12.5	5	18.9	3.63	27.3	5.50	4.0a	1.36
25.0	5	23.5	1.78	35.6	5.32	5.8a	0.54
37.5	5	16.5	1.78	27.7	2.89	3.6a	0.51
50.0	5	21.5	2.05	32.3	2.89	5.3a	0.71
Trend Testb:						p < 0.0070
Testes - Somatic Cells
0	5	14.9	2.13	27.5	1.93	2.4	0.40
12.5	5	15.5	0.75	25.0	2.62	2.4	0.19
25.0	5	22.0	1.38	32.8	1.82	3.8a	0.36
37.5	5	20.3	0.97	30.9	1.34	3.6a	0.29
50.0	5	24.7	2.67	36.4	2.98	4.9a	0.83
Trend Testb:						p = 0.0004

Data based on 100 cells scored per animal

^ap < 0.05; one-tailed t-test

^bLinear regression; significant at p < 0.05