Table 6. Comet Assay Data for Rats Exposed to Cyclophosphamide.

Dose (mg/kg)	Number of Animals	% Tail DNA		Tail Length (Microns)		Olive Tail Moment
		Mean	S.E.	Mean	S.E.	Mean	S.E.
Blood
0	5	6.0	0.90	11.7	0.70	0.7	0.17
2.5	5	5.8	0.11	11.6	0.57	0.6	0.03
5.0	5	5.7	0.07	13.1	0.54	0.7	0.06
10	5	7.6	0.86	13.9	1.12	0.9	0.13
20	5	8.8	0.86	15.7	0.92	1.1a	0.13
Trend Test:						p = 0.0011b
Liver
0	5	20.4	4.41	22.8	3.14	3.8	1.17
2.5	5	28.6	2.53	29.3	1.14	6.4	0.82
5.0	5	25.5	3.31	28.8	1.44	5.2	1.00
10	5	21.6	1.93	27.1	0.67	4.2	0.55
20	5	36.1	9.25	30.5	3.69	8.5	2.40
Trend Test:						p = 0.0565 c
Duodenum
0	5	21.7	3.99	23.7	2.00	3.9	0.78
2.5	5	32.0	5.30	32.4	3.99	6.5d	1.11
5.0	5	33.9	9.43	32.0	3.08	6.7	1.90
10	5	28.5	2.66	29.5	1.98	5.7d	0.47
20	5	37.9	5.75	32.2	2.15	7.4d	1.13
Trend Test:						p = 0.1331 c

Data based on 100 cells scored per animal

^ap < 0.05; one-tailed Mann-Whitney test

^bKendall Correlation; significant at p < 0.05

^cLinear regression; significant at p < 0.05

^dp < 0.05; one-tailed t-test