. Author manuscript; available in PMC: 2012 Dec 12.

Published in final edited form as: J Toxicol Sci. 2010 Apr;35(2):149–162. doi: 10.2131/jts.35.149

Table 7. Comet Assay Data for Mice Treated with Vincristine Sulfate.

Dose (mg/kg)	Number of Animals	% Tail DNA		Tail Length (Microns)		Olive Tail Moment

		Mean	S.E.	Mean	S.E.	Mean	S.E.
Blood

0	5	9.2	0.75	12.6	1.29	1.2	0.12
0.0125	5	8.8	0.88	11.3	1.38	1.3	0.20
0.0250	5	11.9	2.13	14.5	2.12	2.0	0.50
0.0500	5	11.2	1.62	14.3	2.01	1.9	0.42
0.0750	5	11.4	1.30	15.0	0.94	1.9	0.33
Trend Test^a:						p = 0.1297

Liver

0	5	20.2	1.83	24.6	1.28	3.7	0.37
0.0125	5	20.4	1.60	24.2	1.73	3.8	0.42
0.0250	5	20.3	1.80	26.4	0.84	3.9	0.41
0.0500	5	20.8	2.19	27.2	1.89	4.1	0.51
0.0750	5	19.1	1.84	24.8	1.50	3.6	0.41
Trend Test^a:						p = 0.0980

Duodenum

0	5	19.2	6.40	6.6	2.26	0.9	0.43
0.0125	5	17.3	5.72	6.1	2.11	0.7	0.36
0.0250	5	20.6	6.61	6.9	2.42	1.0	0.39
0.0500	5	18.1	3.62	7.0	1.63	0.8	0.22
0.0750	5	29.8	5.72	10.5	1.16	1.6	0.40
Trend Test^a:						p = 0.2227

Data based on 100 cells scored per animal

Linear regression; significant at p < 0.05