Table 8. Comet Assay Data for Rats Exposed to Vincristine Sulfate.

Dose (mg/kg)	Number of Animals	% Tail DNA		Tail Length (Microns)		Olive Tail Moment
		Mean	S.E.	Mean	S.E.	Mean	S.E.
Blood
0	5	8.2	0.63	15.4	0.64	1.1	0.08
0.00625	5	9.3	0.43	14.7	1.23	1.4a	0.11
0.01250	5	8.1	1.05	13.6	0.99	1.1	0.17
0.02500	5	9.3	1.56	14.8	1.39	1.4	0.33
0.03125	5	8.7	1.03	14.4	1.29	1.3	0.23
Trend Testb:						p = 0.5610
Liver
0	5	31.5	6.79	9.1	0.94	1.6	0.49
0.00625	5	25.6	4.48	8.2	0.62	1.2	0.25
0.01250	5	25.1	4.90	6.9	0.90	1.1	0.28
0.02500	5	34.0	2.57	9.4	0.33	1.8	0.17
0.03125	5	28.2	2.52	8.6	0.47	1.3	0.15
Trend Testb:						p = 0.8742
Duodenum
0	5	35.5	2.14	5.9	0.42	1.3	0.07
0.00625	5	36.5	3.38	6.1	0.52	1.4	0.14
0.01250	5	34.2	0.31	6.0	0.20	1.3	0.12
0.02500	5	36.0	5.03	6.0	0.50	1.4	0.17
0.03125	5	37.9	3.31	6.7	0.31	1.4	0.13
Trend Testb:						p = 0.6632

Data based on 100 cells scored per animal

^ap < 0.05; one-tailed t-test

^bLinear regression; significant at p < 0.05