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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Cancer Res Clin Oncol. 2012 Jun 13;138(9):1607–1612. doi: 10.1007/s00432-012-1252-9

Fig 1.

Fig 1

The expression of cyclin D1 in mammary luminal epithelial cells and Leptin deficiency significantly inhibited expression of cyclin D1. a–i. Immunofluorescence analysis of keratin 8 (red) and cyclin D1 (green) in MMTV-Wnt-1 tumors in wild type, ob/ob and db/db mice. Nuclei were counterstained with DAPI (dark blue). Scale bar=100 mm. j. Quantification of CyclinD1 immunoreactive cells in sections of tumors from wild type, ob/ob and db/db mice. Only cells expressing nuclear cyclin D1 were analyzed. Data are presented as mean ± SEM.