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Case 2: Core biopsy for the liver of a 63-year-old patient with a rapidly enlarging liver. Panel A: Liver biopsy with metastatic adenocarcinoma. Liver tissue (top left) is diffusely infiltrated by malignant cells (bottom right) (hematoxylin-eosin stain; 10×). Panel B: Case 2: High-power view of tumor cells with a high nuclear-to-cytoplasmic ratio, prominent nucleoli, and frequent mitosis (black circles) (hematoxylin-eosin stain; 40×).
