Table 1.

Summary of reported cases of radiological occult cancer infiltration of the liver

Presenting symptoms	Age (years)	Prior history of cancer	Radiological test	Reported findings	Other lab test	Biopsy/Autopsy results	Reference number
Nausea, vomiting, abdominal pain	36	Ductal carcinoma 9 months prior	CT	No abdominal lesions	Increased LFTs	Breast cancer	3
Anorexia and general fatigue	46	Mycosis fungoides	CT and US	Normal liver	20-fold increased LFTs	Mycosis fungoides	13
Mild fever with elevated LFTs	50	None	CT	Hepatomegaly	Elevated LFTs, low plts and HCT	Peripheral T-cell lymphoma	12
Abdominal pain, decreased appetite	54	None	CT and US	Hepatomegaly and ascites	Low HCT	Small-cell lung cancer	10
Worsening ascites, jaundice, and hematochezia	54	Breast cancer 9 years prior	CT US	Probable benign cysts, ascites	Elevated LFTs	Poorly differentiated adenocarcinoma	4
Altered liver test	57	None	CT and US	Heterogeneous liver parenchyma	Thrombocytopenia	Breast lobular carcinoma	5
Clinical signs of hepatocellular injury	59	Renal cell carcinoma	Liver MRI	Hepatomegaly	None reported	Renal cell carcinoma	14
Anorexia and abdominal distension	62	None	US and CT	Hepatomegaly and ascites	Elevated CA-125	Melanoma	15
Abnormal liver function	62	None	CT and MRI	Marked liver enlargement, no lesions	Increased LFT	Small-cell lung cancer	9
Acute hepatic failure	68	None	CT scan	Negative	High LFTs	Metastatic prostatic carcinoma.	16
Gastrointestinal hemorrhage	69	None	CT	No liver metastatic disease	LFT elevation	Urothelial carcinoma	8
Acute severe hepatic failure	77	T-cell lymphoma	CT and US	Homogeneous enlarged liver, no ascites	Bili 9.1, increase LFTs	Small cell carcinoma	11
Infants with hepatosplenomegaly	<1	None	CT /MRI	Liver enlargement	No biogenic amines	Neuroblastoma	6

Bili = bilirubin; CA = cancer antigen; CT = computed tomography; HCT = hematocrit; LFT = liver function test; plts = platelets; US = ultrasound; MRI = magnetic resonance imaging.