Table 2.
Kinetic parameters of Sup35-NM and Ure2p aggregation reactions
| Protein | Parameters | Non seeded | Sup35-NM Fibrils | Sup35-Nm IBs | Ure2p IBs |
|---|---|---|---|---|---|
| Sup35-NM |
kn /106·s-1 |
0.35 |
1.07 |
1.00 |
0.45 |
| |
ke /M-1·s-1 |
37.54 |
36.08 |
36.67 |
36.07 |
| |
c·ke /106·s-1 |
750.83 |
721.50 |
733.33 |
721.33 |
| |
t0 /s |
124.0 |
102.5 |
98.6 |
123.0 |
| |
t1/2 /s |
169.9 |
150.1 |
149.6 |
171.0 |
| |
t1 /s |
215.8 |
197.8 |
200.7 |
219.1 |
| |
|
|
|
|
|
|
Protein |
Parameters |
Non seeded |
Ure2p Fibrils |
Ure2p IBs |
Sup35-IBs |
| Ure2p |
kn/106·s-1 |
2.13 |
11.46 |
14.24 |
2.62 |
| |
ke /M-1·s-1 |
22.33 |
23.40 |
21.49 |
22.53 |
|
c·ke /106·s-1 |
446.67 |
468.00 |
429.83 |
450.50 |
|
|
t0 /s |
122.9 |
60.8 |
54.9 |
114.5 |
|
|
t1/2 /s |
199.9 |
131.2 |
129.5 |
190.3 |
|
| t1 /s | 276.8 | 201.6 | 204.2 | 266.0 |