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. 2012 Oct 3;6:32. doi: 10.1186/1753-2000-6-32

Table 5.

Percentage at risk for impaired health related quality of life (TACQoL): patients with congenital hypothyroidism (CH) versus the norm population

  Total CH Severe CH Moderate/Mild CH Norm population
Child-report
 
 
 
 
 
n = 82
n = 41
n = 41
n = 449
Physical Functioning
40%
46% *
34%
25%
Motor Functioning
48% **
50% *
46% *
25%
Autonomy
38% **
46% **
29%
25%
Cognitive functioning
40% *
57% **
25%
25%
Social Functioning
34%
41%
28%
25%
Positive emotions
45% *
42%
47% *
25%
Negative emotions
30%
36%
25%
25%
Parent-report
 
 
 
 
 
n = 82
n = 41
n = 41
n = 465
Physical Functioning
34%
37%
32%
25%
Motor Functioning
55% **
61% **
49%*
25%
Autonomy
27%
32%
22%
25%
Cognitive functioning
56% **
61% **
51%*
25%
Social Functioning
29%
34%
24%
25%
Positive emotions
34%
37%
25%
25%
Negative emotions 38% 39% 37% 25%

1 25 th Percentiles of norm population are not exact 25% due to distribution of scale scores; percentiles approach 25th, ranging from 17th – 31st percentile.

*p < 0.007: difference between CH patients and norm population according to Chi-square test **p < 0.0001: difference between CH patients and norm population according to Chi-square test.