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. 2012 Dec 12;7(12):e51215. doi: 10.1371/journal.pone.0051215

Figure 6. α-GalCer does not induce expansion of CD25+foxp3+ regulatory T (Treg) cells.

Figure 6

Mice were immunized with GPI peptide and treated with either DMSO or α-GalCer, then euthanized on day 6 or 10 and dLN cells were harvested. (A) Foxp3+ T reg cells were detected as TCRβ, foxp3- and CD25-positive cells by flow cytometry. (B) Proportion of foxp3+ CD25+ cells among TCRβ+ αβ T cells. Data are mean±SD. *p<0.05, by Man-Whitney analysis.