Table 1. Summary of short and long term effect of subcutaneous aerogel implant on local tissue.
Incubation PeriodResponse | Two weeks | Twenty months | ||
Clear | Pigmented | Clear | Pigmented | |
Inflammation | Mild | Mild | Mild | Mild |
Fibrosis | Mild | Mild | Mild | Mild |
Infection | None | None | None | None |
Implant travel | None | None | None | None |
Age of rat at time of extraction | ∼3 months | ∼2 years |
Slides from both control and implant-containing rats were reviewed blindly by pathologist, specifically looking for signs of inflammation, infection, fibrosis, and implant travel.