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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: Cancer Res. 2012 Sep 17;72(22):5912–5920. doi: 10.1158/0008-5472.CAN-12-2329

Fig. 2.

Fig. 2

Phenotypic changes associated with Hh signaling in HBx positive and negative cells with or without GDC-0449. (A) Representative images of HBx expressing cells that migrated through Matrigel basement membrane (200x). (B) Quantification of the results in panel A (mean expression ± S.D. of 3 assays). Cells were treated with DMSO (dark bars) or with GDC-0449 (light bars): *p<0.01; **p<0.02. (C) Anchorage independent growth of Huh7X and HepG2X with or without GDC-0449. (D) Quantification of the results in panel C (mean expression ± S.D. of 3 assays). Cells were treated with DMSO (dark bars) or with GDC-0449 (light bars): *p<0.01; **p<0.03.