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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: Stat Med. 2012 Jul 17;32(1):131–141. doi: 10.1002/sim.5491

Table I.

Drug combinations used in Phase 1 trial of lomeguatrib and temozolomide.

Dosage
Agent d 1 d 2 d 3 d 4 d 5 d 6 d 7 d 8
Lomeguatrib (mg/m2/day) 10 10 10 10 10 10 20 40
Temozolomide (mg/m2/day) 50 75 100 125 150 175 125 125