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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Neuropharmacology. 2012 Sep 13;65:134–142. doi: 10.1016/j.neuropharm.2012.09.004

Figure 2. WD increases presynaptic function at IC-BLA afferents.

Figure 2

A) Diagram representing relative placements of stimulating (IC-BLA) and recording electrodes (BLA) for electrophysiology experiments. B) Decreased PPRs during WD indicate increased release probability at multiple interstimulus intervals: 25ms [CON, 0.37 ± 0.05, n = 16; CIE, 0.48 ± 0.06, n = 10; WD, 0.08 ± 0.06, n = 11; F(2,34) = 9.464, p < 0.05], 50ms [CON, 0.23 ± 0.04, n = 16; CIE, 0.28 ± 0.04, n = 14; WD, 0.01 ± 0.05, n = 15; F(2,42) = 9.488 p > 0.05], 100ms [CON, 0.10 ± 0.05, n = 15; CIE, 0.17 ± 0.04, n = 13, WD, −0.02 ± 0.04 n =15; F(2,40) = 4.117 p > 0.05)], One Way ANOVA’s, Newman-Keuls post hoc tests. ### = significant vs. CON; # ,** = significant vs. CIE. C) Representative traces of PPR recordings (50 ms) scaled to second peak amplitude during each treatment condition.