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The vasculature of cancerous tissues can be more leaky than that of healthy tissues. This difference in leakiness can be exploited in anticancer drug delivery. Vasculature of the tissue on the left is normal while the tissue on the right is leaky. The nanoparticles passively enter through the leaky vasculature into the tumor tissue due to the enhanced permeability and retention (EPR) effect. (Illustrated by Samantha L. Lindberg).
