Figure 1. GBGT1 genes and encoded proteins from Forssman-positive and negative species.

The annotated entries of the GBGT1 genes and their encoded proteins were extracted from the Ensembl database and categorized by species. a) The Forssman positivity and negativity are indicated by (+) and (−), respectively, when it is known for the species, whereas a question mark (?) shows unknown. b) In order to facilitate the identification of partial genes and pseudogenes, the numbers of the deduced amino acid residues of the individual proteins are indicated. c) The amino acid residues corresponding to the codons between 258 and 263 of the mouse FS, were also extracted, and the residues that are different from the consensus FYYGGA sequence are indicated in bold. d) Additional useful information is added in the Remarks. Potential mechanisms of Forssman negativity deduced from the in silico analysis are shown in bold.