Table 4.

Relating our findings with those existing works

	Reused	Specialized	Previous works
Static	'Date' hubs	'Family' hubs	Han et al., 2004 [3]; Komurov and White, 2007 [7]
	Inter-modular	Intra-modular	Yu et al., 2007 [10]
	Category 2	Category 1	Patil et al., 2011 [11]
	Essential		Pereira-Leal, 2006 [6]
Dynamic		'Party' hubs	Han et al., 2004 [3]; Komurov and White, 2007 [7]
		Intra-modular	Yu et al., 2007 [10]

Our classification of proteins is based on their participation in complexes into static "reused" and static/dynamic "specialized" proteins We relate this to the classification of hubs from previous works.