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Correlation map for MtIDH1. The region around S213, including the ARS-like region just above it, shows negative correlations not seen in any S2-type IDH simulated here. The ARS-like region in particular shows negative correlations, and so does S213 and its immediate vicinity. This movement may be biologically relevant, as it does not appear in any other IDH simulation, particularly S2-IDHs, and is unlikely to be obtained by chance.
