Table 2.

Test performance evaluation of plasma DNA quantification by real-time qPCR.

Cut-off	Sensitivity	95% CI	Specificity	95% CI	+LR	-LR
≥ 0.91	100	76.7-100.0	0	0.0-20.8	1.00
≥ 1.98	92.9	66.1-98.8	62.5	35.5-84.7	2.48	0.11
≥ 2.78*	85.7	57.2-97.8	75.0	47.6-92.6	3.43	0.19
≥ 3.36	78.6	49.2-95.1	81.3	54.3-95.7	4.19	0.26
≥ 5.39	64.3	35.2-87.1	87.5	61.6-98.1	5.14	0.41
≥ 7	50	23.1-76.9	100	79.2-100.0		0.50

*The cut-off value corresponding with the highest average of sensitivity and specificity. +LR is a positive and -LR is a negative likelihood ratio.