Table 1.
Tumor marker concentration in pleural fluid (P), serum (S), and the P/S ratio (R) in patients with malignant vs.
| Malignant effusion (n = 36) | Non-malignant effusion (n = 38) | P | |
|---|---|---|---|
| CA-125(P) | 965.9 (412.9-1790.5) | 518.5 (297.7-796.6) | NS |
| CEA(P) | 12.1 (1.9-79.2) | 1.1 (0.8-1.6) | < 0.001 |
| CYFRA 21-1(P) | 27.5 (14.8-213.6) | 12.8 (5.0-31.5) | < 0.05 |
| NSE(P) | 2.7 (0.9-10.5) | 1.0 (0.2-4.3) | < 0.05 |
| CA-125(S) | 180.7 (68.4-404.8) | 135.8 (60.6-191.4) | NS |
| CEA(S) | 4.1 (1.7-28.1) | 2.3 (1.5-3.4) | < 0.05 |
| CYFRA 21-1(S) | 4.6 (2.1-16.6) | 1.9 (1.2-2.7) | < 0.001 |
| NSE(S) | 15.8 (10.9-30.5) | 11.9 (8.1-18.4) | NS |
| CA-125(R) | 4.6 (2.6-7.1) | 3.7 (2.6-6.9) | NS |
| CEA(R) | 1.4 (0.8-3.9) | 0.5 (0.4-0.7) | < 0.001 |
| CYFRA 21-1(R) | 0.1 (0.06-0.8) | 0.1 (0.02-0.3) | NS |
| NSE(R) | 6.9 (2.1-11.1) | 6.9 (2.6-20.5) | NS |
nonmalignant PE.
Values are presented as median (with IQR in parenthesis). CA-125 (mU/ml), CEA (μg/ml), CYFRA 21-1 (ng/ml), and NSE (ng/ml).