Table 1.

Comparing average number of pathways crossed from the top 20 routes in two methods.

Source	Target	switchmrsd	switchneato	switchmetaroute	switchcmpf1	switchcmpf2
glucose	pyruvate	1.95	1.5	2.95	0	0.85
glutamate	proline	2.45	2.79	0.47	0	0.3
oxaloacetate	malate	1.75	1.33	0.65	0	0.95
glutamate	arginine	2.45	2.05	0.4	0	0
cdp-diacyl-glycerol	cardiolipin	1.75	1.0	1.8	0	0.1
gtp	riboflavin	2	1.78	4.25	0.95	1.05
allantoin	glyoxylate	4.3	2.0	*	1.85	3.15
rhamnose	pyruvate	1.9	0.875	1.1	0.85	1

CMPF₁ uses static penalty and CMPF₂ uses dynamic penalty. (*denotes no path found by method)