Table 2.
The ρdiff scores of the 1st and 1000th ranked SNP pairs and their associated P-values
| Complete set of SNPs (355882 SNPs) | |||||
|---|---|---|---|---|---|
| Disease | 1stρdiff | 1stP-value | 1000thρdiff | 1000thP-value | Avg. ρdiff± SD |
| BD | 0.2878 | 1.1410e-7 | 0.2680 | 3.4206e-7 | 0.2718±0.0035 |
| CAD | 0.9317 | <2.2204e-16 | 0.9132 | <2.2204e-16 | 0.9171±0.0031 |
| CD | 0.3085 | 3.6109e-8 | 0.2849 | 1.3351e-7 | 0.2887±0.0034 |
| HT | 0.2834 | 1.4510e-7 | 0.2626 | 4.6022e-7 | 0.2667±0.0037 |
| RA | 0.9042 | <2.2204e-16 | 0.8866 | <2.2204e-16 | 0.8903±0.0031 |
| T1D | 1.0731 | <2.2204e-16 | 0.9996 | <2.2204e-16 | 1.0040±0.0056 |
| T2D | 0.3338 | 8.8226e-9 | 0.2159 | 6.1867e-6 | 0.2198±0.0052 |
| Gene-only SNPs (176148 SNPs) | |||||
| Disease | 1stρdiff | 1stP-value | 1000thρdiff | 1000thP-value | Avg. ρdiff± SD |
| BD | 0.2447 | 1.2445e-6 | 0.2224 | 4.2957e-6 | 0.2259±0.0032 |
| CAD | 0.9294 | <2.2204e-16 | 0.9102 | <2.2204e-16 | 0.9143±0.0035 |
| CD | 0.2653 | 3.9790e-7 | 0.2248 | 3.7769e-6 | 0.2280±0.0033 |
| HT | 0.1793 | 4.7229e-5 | 0.1561 | 1.7142e-4 | 0.1605±0.0043 |
| RA | 0.9040 | <2.2204e-16 | 0.8832 | <2.2204e-16 | 0.8875±0.0036 |
| T1D | 1.0731 | <2.2204e-16 | 0.9957 | <2.2204e-16 | 1.0007±0.0061 |
| T2D | 0.3338 | 8.8226e-9 | 0.2127 | 7.3731e-6 | 0.2168±0.0052 |
The highest and the lowest ρdiff scores including their associated P-values are displayed with the average scores of top 1000 SNP pairs from the analyses of WTCCC.